The Endo16 model of cis-regulatory control
Diagram
The logical model of the cis-regulatory control of the Endo16 gene
(see refs below) from S. purpuratus was entered into NetBuilder and its output
evaluated for different combinations of input values. Some of the simulation results
are found on the next page.
Yuh, C.-H., Bolouri, H., and Davidson, E. H. Genomic
cis-regulatory logic: experimental and computational analysis of a sea urchin
gene. Science 279, 1896-1902 (1998)
Yuh, C.-H.,
Bolouri, H., and Davidson, E. H. Cis-regulatory logic in the endo16 gene:
switching from a specification to a differentiation mode of control. Development
128, 617-629 (2001)